Abstract: Early detection and treatment of active tuberculosis (TB) and latent tuberculosis infection (LTBI), are a priority in the fight against TB. TB continues to be the leading cause of death in HIV-infected individuals and, according to the national guidelines, TB screening is mandatory in these patients. In 2009 a Central Hospital Infections Unit (responsible for a region population of 350.000 inhabitants), established a protocol with a TB outpatient clinic aiming to decentralize the screening, improving its compliance and health care access. This study aim to evaluate the gain of the protocol, address in two main questions: what was the program compliance and risk factors to fail the screening? Did it increase case detection?